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Article

Deciphering intratumor heterogeneity using cancer genome analysis.

Human genetics - 1 Jun 2016

Ryu Daeun, Joung Je-Gun, Kim Nayoung K D, Kim Kyu-Tae, Park Woong-Yang

Abstract excerpt

Intratumor heterogeneity within individual cancer tissues underlies the numerous phenotypes of cancer. Tumor subclones ultimately affect therapeutic outcomes due to their distinct molecular features. Drug-resistant subclones are present at a low frequency in tissues at the time of biopsy, but can also arise as a result of acquired somatic mutations. A number of different approaches have been utilized to...

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PMID: 27126234
DOI: 10.1007/s00439-016-1670-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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