Article

Genetically predicted causal associations between 152 blood-related exposures and pan-cancer in the framework of prediction, prevention and personalized medicine: a study integrating Mendelian randomization and bioinformatics

2024-01-03

Abstract excerpt

<h4>Objective: </h4> Blood serves as a powerful tool for monitoring the intricate landscape of cancer development. Previous studies have emerged, suggesting that hematologic indicators hold promise in predicting the onset of malignancy. This present investigation aims to delve into the underlying causal connections between blood-related indicators and pan-cancer, further elucidating the potential impact of disease...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cdf10f6d-8104-5844-9e86-fb94478342a2
DOI: 10.21203/rs.3.rs-3774776/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetically predicted causal associations between 152 blood-related exposures and pan-cancer in the framework of prediction, prevention and personalized medicine: a study integrating Mendelian randomization and bioinformaticsDOI 10.21203/rs.3.rs-3774776/v1Read

Prospective Mendelian Randomization Study of Ancestry-Specific Blood-Cell Genetics in Predicting Pan-Cancer Risk Across 28 Malignant NeoplasmsSemantic proximity Read

Prospective study on the association between 36 human blood cell traits and pan-cancer outcomes: a mendelian randomization analysis.Semantic proximity Read

Phenome-wide Mendelian randomisation analysis of 378,142 cases reveals risk factors for eight common cancers.Semantic proximity Read

Assessing the Causal Impact of the Circulating Proteome on Susceptibility to Gastrointestinal Cancer-Associated CharacteristicsSemantic proximity Read

35 blood and urine biomarkers and digestive system cancers: A two-sample Mendelian randomization study.Semantic proximity Read

SUMMER: A Practical Tool for Identifying Factors and Biomarkers Associated with Pan-cancer Survival.Semantic proximity Read

Pan-cancer analysis demonstrates that integrating polygenic risk scores with modifiable risk factors improves risk predictionSemantic proximity Read

Risk of Second Primary Cancers After a Diagnosis of First Primary Cancer: A Pan-Cancer Analysis and Mendelian Randomization StudySemantic proximity Read

Causal effects of blood and urinary biomarkers on cancer risk: A Mendelian randomization study.Semantic proximity Read

Blood Lipid Metabolic Profiles and Causal Links to Site-Specific Cancer Risks: A Mendelian Randomization Study.Semantic proximity Read

SUMMER: a Mendelian randomization interactive server to systematically evaluate the causal effects of risk factors and circulating biomarkers on pan-cancer survival.Semantic proximity Read

Integrating Mendelian randomization and literature-mined evidence for breast cancer risk factorsSemantic proximity Read