Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Causal effects of blood and urinary biomarkers on cancer risk: A Mendelian randomization study.

The Journal of international medical research - 1 Jul 2026

Leng Lina, Li Ying

Abstract excerpt

ObjectiveObservational studies have linked various serum and urinary biomarkers to cancer risk, but confounding and reverse causation limit causal inference. This study aimed to investigate the causal effects of 35 circulating biomarkers on the risk of 13 site-specific cancers.MethodsWe performed a comprehensive two-sample Mendelian randomization analysis using genetic instruments for 35 biomarkers from the UK...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Causality
Share to Finland

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mendelian Randomization Analysis

Share to Neoplasms

Share to Risk Assessment

Share to UK Biobank

Share to United Kingdom

Source

Open in PubMed Open full text

Identifiers

PMID: 42403162
DOI: 10.1177/03000605261466576
PMCID: PMC13338554

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Causal effects of blood and urinary biomarkers on cancer risk: A Mendelian randomization study.PMID 42403162Read ↗

35 blood and urine biomarkers and digestive system cancers: A two-sample Mendelian randomization study.Semantic proximity Read ↗

The causal relationship of serum uric acid on colorectal cancer: A Mendelian randomization study.Semantic proximity Read ↗

Mendelian randomization: A powerful method to determine causality of biomarkers in diseasesSemantic proximity Read ↗

Causal association of serum biomarkers with oral cavity and oropharyngeal cancer: a mendelian randomization study.Semantic proximity Read ↗

Bidirectional Mendelian randomization analysis investigating causal associations between 35 blood and urine biomarkers and oral lichen planus.Semantic proximity Read ↗

Genetically Raised Circulating Bilirubin Levels and Risk of Ten Cancers: A Mendelian Randomization Study.Semantic proximity Read ↗

Urinary biomarkers and cardiovascular outcomes in the UK Biobank: observational and Mendelian randomization analysesSemantic proximity Read ↗

Associations of Circulating Biomarkers with Disease Risks: a Two-Sample Mendelian Randomization StudySemantic proximity Read ↗

Causal inference study of the effect of serum enzymes on breast cancer risk: Two-sample Mendelian randomization.Semantic proximity Read ↗

Application of Mendelian randomization analysis in investigating the genetic background of blood biomarkers for colorectal cancer.Semantic proximity Read ↗

Assessing the Causal Impact of the Circulating Proteome on Susceptibility to Gastrointestinal Cancer-Associated CharacteristicsSemantic proximity Read ↗

Systematic review of Mendelian randomization studies on risk of cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.