Article

HCS-Splice: A High-Content Screening Method to Advance the Discovery of RNA Splicing-Modulating Therapeutics

2023-06-26

Abstract excerpt

Nucleic acid therapeutics are witnessing an impressive acceleration in recent years. They work through multiple mechanisms of action, including downregulation of gene expression and modulation of RNA splicing. While several drugs based on the former mechanism have been approved, few target the latter, despite the promise of RNA splicing modulation. To improve our ability to discover novel RNA splicing-modulating t...

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Literature Corpus work: cdcf8b36-2eb9-573a-acc2-81ce72c92778
DOI: 10.20944/preprints202306.1818.v1

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