Article

Splicing-dependent transcriptional activation

2022-09-17

Abstract excerpt

<h4>Summary</h4> Transcription and splicing are intrinsically coupled. Transcription dynamics regulate splicing, and splicing feeds back to transcription initiation to jointly determine gene expression profiles. A recently described phenomenon called exon-mediated activation of transcription starts (EMATS) shows that splicing of internal exons can regulate transcription initiation and activate cryptic promoters....

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Literature Corpus work: 83ae60db-3c52-54c4-a23b-c980c9371a94
DOI: 10.1101/2022.09.16.508316

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