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Article

Whole-exome sequencing of a pedigree segregating asthma.

BMC medical genetics - 9 Oct 2012

DeWan Andrew T, Egan Kathryn Brigham, Hellenbrand Karen, Sorrentino Keli, Pizzoferrato Nicole, Walsh Kyle M, Bracken Michael B

Abstract excerpt

BACKGROUND: Despite the success of genome-wide association studies for asthma, few, if any, definitively causal variants have been identified and there is still a substantial portion of the heritability of the disease yet to be discovered. Some of this "missing heritability" may be accounted for by family-specific coding variants found to be segregating with asthma. METHODS: To identify family-specific variants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23046476
DOI: 10.1186/1471-2350-13-95
PMCID: PMC3563469

Genes

CBLB
KALRN

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