Article

Duplications of human longevity-associated genes across placental mammals

2023-05-02

Abstract excerpt

Natural selection has shaped a wide range of lifespans across mammals, with a few long-lived species showing negligible signs of ageing. Approaches used to elucidate the genetic mechanisms underlying mammalian longevity usually involve phylogenetic selection tests on candidate genes, analyses of differential gene expression between age cohorts or species, and measuring age-related epigenetic changes. However, the...

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Literature Corpus work: cd8eb4a8-8f1b-5ce7-8d6a-2e7b85dde26a
DOI: 10.1101/2023.05.02.539026

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