Article

Age-specific control and Alzheimer’s disease reference curves and z-scores for glial fibrillary acidic protein in blood

2024-12-05

Abstract excerpt

<h4>Background</h4> Serum glial fibrillary acidic protein (GFAP) is a biomarker for astrocytic injury and astrogliosis. Concentrations are elevated in numerous neurological disorders, including a pronounced increase in Alzheimer’s disease (AD). However, GFAP levels in the serum also increase with age. Consequently, the integration of GFAP levels into clinical routine and their interpretation demands age-adjusted...

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Literature Corpus work: cd7d4d0d-2138-5388-a38d-4629a7bc3cd8
DOI: 10.1101/2024.12.04.24318285

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