Article

Glial fibrillary acidic protein, neurofilament light, matrix metalloprotease 3 and fatty acid binding protein 4 as non-invasive brain tumor biomarkers

2024-02-09

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Gliomas are aggressive malignant tumors, with poor prognosis. There is an unmet need for the discovery of new, non-invasive biomarkers for differential diagnosis, prognosis, and management of brain tumors. Our objective is to validate four plasma biomarkers – glial fibrillary acidic protein (GFAP), neurofilament light (NEFL), matrix metalloprotease 3 (MMP3) and...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bbb03e99-db9c-5a6b-bb60-2bc086ec59d5
DOI: 10.21203/rs.3.rs-3918607/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Glial fibrillary acidic protein, neurofilament light, matrix metalloprotease 3 and fatty acid binding protein 4 as non-invasive brain tumor biomarkersDOI 10.21203/rs.3.rs-3918607/v1Read

Quantitative Proteomic Analysis of Meningiomas for the Identification of Surrogate Protein MarkersSemantic proximity Read

Identification of astrocytomas through serum protein fingerprint using MALDI-TOF MS and machine learningSemantic proximity Read

Glioma Pathophysiology: Insights Emerging from ProteomicsSemantic proximity Read

Unravelling the role of Exosomes as early non-invasive predictors of disease state in GlioblastomaSemantic proximity Read

Clinical Implications of Inflammation-Mediated Dysregulation of Glial Cell Fate: A Systematic Review for Early Brain Tumor Risk Detection and Improved Patient OutcomesSemantic proximity Read

Glioblastoma: Is There Any Blood Biomarker with True Clinical Relevance?Semantic proximity Read

Importance of GFAP isoform‐specific analyses in astrocytomaSemantic proximity Read

Identification of Astrocytoma Blood Serum Protein ProfileSemantic proximity Read

A large-scale targeted proteomics of serum and tissue shows the utility of classifying high grade and low grade meningioma tumorsSemantic proximity Read

Early Detection of Glioma: Investigating Inflammatory Markers (CRP), Kidney, and Liver Function.Semantic proximity Read

Clinical Characteristics and Magnetic Resonance Imaging-Based Prediction of the KLF4K409Q Mutation in Meningioma.Semantic proximity Read

Quantification of blood glial fibrillary acidic protein using a second-generation microfluidic assay. Validation and comparative analysis with two established assaysSemantic proximity Read