Article

Radiation-induced rescue effect on human breast carcinoma cells is regulated by macrophages

2023-08-05

Abstract excerpt

The susceptibility of cancer cells to DNA damages is influenced by their microenvironment. For example, unirradiated neighbors of irradiated cells can produce signals that reduce DNA damages. This phenomenon, known as Radiation-Induced Rescue Effect (RIRE), has profound implications on the efficacy of radiotherapy. Using bystander cells cocultured with mock-irradiated cells as a control, we demonstrated, for the f...

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Literature Corpus work: cd7d2e22-3e19-5fa8-818c-5781b9eb74f1
DOI: 10.1101/2023.08.02.551610

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