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A Kinetic-Based Model of Radiation-Induced Intercellular Signalling

22 Jan 2013

Abstract excerpt

It is now widely accepted that intercellular communication can cause significant variations in cellular responses to genotoxic stress. The radiation-induced bystander effect is a prime example of this effect, where cells shielded from radiation exposure see a significant reduction in survival when cultured with irradiated cells. However, there is a lack of robust, quantitative models of this effect which are...

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PMID: 23349919
DOI: 10.1371/journal.pone.0054526

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