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Article

Intercellular and intracellular signaling pathways mediating ionizing radiation-induced bystander effects.

Journal of radiation research - 1 Mar 2007

Hamada Nobuyuki, Matsumoto Hideki, Hara Takamitsu, Kobayashi Yasuhiko

Abstract excerpt

A rapidly growing body of experimental evidence indicates that ionizing radiation induces biological effects in non-irradiated bystander cells that have received signals from adjacent or distant irradiated cells. This phenomenon, which has been termed the ionizing radiation-induced bystander effect, challenges the long-standing paradigm that radiation traversal through the nucleus of a cell is a prerequisite to...

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Identifiers

PMID: 17327686
DOI: 10.1269/jrr.06084

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