Article

Identification of Potent Small Molecule Inhibitors of SARS-CoV-2 Entry

2021-08-05

Abstract excerpt

<h4>ABSTRACT</h4> The severe acute respiratory syndrome coronavirus 2 responsible for COVID-19 remains a persistent threat to mankind, especially for the immunocompromised and elderly for which the vaccine may have limited effectiveness. Entry of SARS-CoV-2 requires a high affinity interaction of the viral spike protein with the cellular receptor angiotensin-converting enzyme 2. Novel mutations on the spike prote...

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Literature Corpus work: cd70a6b5-1be4-5f2d-a735-da1b7b046e43
DOI: 10.1101/2021.08.05.455262

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