Article
Targeting SARS-CoV-2 and host cell receptor interactions.
Antiviral research - 1 Feb 2023
Lim Siew Pheng
Abstract excerpt
Despite the availability of vaccines and therapeutics, continual genetic alterations render the severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) a persistent threat, particularly for the immunocompromised and elderly. Through interactions of its spike (S) protein with different receptors and coreceptors on host cell surfaces, the virus enters the cell either via fusion with the plasma membrane or...
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