Anti-viral chimeric protein RetroMAD1™ potently block SARS-CoV-2 viral entry and propagation

Abstract excerpt

COVID-19 is a disease caused by the highly transmissible and pathogenic SARS-CoV-2 virus. Since its first case was documented in 2019, it has rapidly widespread and has caused millions of deaths worldwide. Many intervention strategies targeting these proteins have been developed. However, frequently mutation of SARS-CoV-2 poses a challenge to the effectiveness of current treatments. Therefore, it is critical to de...

Topics

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• Amino Acid Sequence
• Animal Virus Infections Studies
• Computational Drug Discovery Methods
• COVID-19
• COVID-19 Clinical Research Studies
• interferon and immune responses
• Mutation
• SARS-CoV-2 and COVID-19 Research

Identifiers and source

Literature Corpus work

dbf9f786-ff8f-510c-980c-24454e0af03f

DOI

10.21203/rs.3.rs-2712307/v1