Article

A novel, minimally invasive diagnostic test for KIT exon 11 internal tandem duplications in canine cutaneous mast cell tumours I: Assay development

2026-04-10

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> In canine cutaneous mast cell tumours (cMCTs), Internal Tandem Duplications (ITDs) of exon 11 of the <italic>KIT</italic> receptor tyrosine kinase are associated with higher histological grade and greater risk of metastasis. They also predict response to tyrosine kinase inhibitors (TKIs). Assessment of <italic>KIT</italic> mutation status provides importan...

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Literature Corpus work: cd69e453-d38e-58ab-b38d-dd41fcdeef17
DOI: 10.21203/rs.3.rs-9368633/v1

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