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Mitochondrial dysfunction underlies cardiac contractility and growth defects in a zebrafish model of <i>NAA15</i> -related heart disease

2025-08-06

Abstract excerpt

Delineating the genetic and environmental instigators of congenital heart disease (CHD), affecting up to 1% of newborns, will improve preventative, diagnostic, and therapeutic efforts to mitigate disease outcomes. Although mutations in NAA15 , which encodes the auxiliary subunit of N-alpha-acetyltransferase A (NatA), are associated with CHD in humans, vertebrate animal models of NAA15 -related heart disease have...

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Identifiers and source

Literature Corpus work
cd69a85d-4a3d-56e0-840f-40828f885401
DOI
10.1101/2025.08.04.668548
Open publication

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