Article

Zebrafish <i>acta1b</i> as a Candidate for Modeling Human Actin Cardiomyopathies

2023-08-30

Abstract excerpt

Heart failure is the leading cause of mortality worldwide, primarily associated with cardiovascular disease. Many heart muscle diseases are caused by mutations in genes that encode contractile proteins, including cardiac actin mutations. Zebrafish are an advantageous system for modelling cardiac diseases due to their ability to develop without a functional heart throughout embryonic development. However, genome du...

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Literature Corpus work: f39a4556-e12c-5ad5-bf93-8b66d583a858
DOI: 10.1101/2023.08.29.555390

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