Article

AI-based Predictive Signaling Pathway Profiling in Cardiac Fibrosis Suggests a Novel Combinatorial Treatment Strategy

2025-12-04

Abstract excerpt

<h4>Background</h4> Cardiovascular disease (CVD) remains the leading cause of global mortality, with myocardial fibrosis characterized by excessive extracellular matrix (ECM) deposition representing a common endpoint associated with progressive cardiac dysfunction. While studies in animal models of heart disease suggest that preventing or reducing fibrosis can antagonize negative ventricular remodeling, current t...

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Literature Corpus work: cd6445c7-729a-5af8-b120-60413e08ded3
DOI: 10.64898/2025.12.04.692460

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