Article

Which actin genes are necessary for zebrafish heart development and function?

2020-08-26

Abstract excerpt

Heart failure is the number one cause of mortality in the world, contributed to by cardiovascular disease. Many diseases of the heart muscle are caused by mutations in genes encoding contractile proteins, including cardiac actin mutations. Zebrafish are an advantageous system for modeling cardiac disease since embryos can develop without a functional heart. However, genome duplication in the teleost lineage create...

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Literature Corpus work: cd4c558b-09ff-5454-8d4c-a077c9e869a2
DOI: 10.1101/2020.08.25.266932

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