Article
Zebrafish Congenital Heart Disease Models: Opportunities and Challenges.
International journal of molecular sciences - 29 May 2024
Yang Dixuan, Jian Zhenjie, Tang Changfa, Chen Zhanglin, Zhou Zuoqiong, Zheng Lan, Peng Xiyang
Abstract excerpt
Congenital heart defects (CHDs) are common human birth defects. Genetic mutations potentially cause the exhibition of various pathological phenotypes associated with CHDs, occurring alone or as part of certain syndromes. Zebrafish, a model organism with a strong molecular conservation similar to humans, is commonly used in studies on cardiovascular diseases owing to its advantageous features, such as a similarity...
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