Article
Targeting Neutrophil Extracellular Traps to inhibit Colon Cancer Tumor Necrosis and Metastasis
2025-06-03
Abstract excerpt
Necrosis, conventionally thought of as a passive consequence of aggressive tumor growth, is associated with poor prognosis in colorectal cancer (CRC). We recently discovered that necrosis can be caused by neutrophils and neutrophil extracellular traps (NETs) aggregates driving vascular occlusion within the tumor vasculature in models of breast cancer. Here, we evaluated the role of NETs in inducing necrosis and me...
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Identifiers and source
- Literature Corpus work
- cd3e2386-2667-5c77-a3cd-36ab68ecfcde
- DOI
- 10.1101/2025.05.30.657122