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Article

Ref-1 Redox Activity Alters Cancer Cell Metabolism in Pancreatic Cancer: Exploiting This Novel Finding as a Potential Target  

2020-12-15

Abstract excerpt

<title>Abstract</title> <p><underline>Background</underline>: Pancreatic cancer is a complex disease with a desmoplastic stroma, extreme hypoxia, and inherent resistance to therapy. Understanding the signaling and adaptive response of such an aggressive cancer is key to making advances in therapeutic efficacy. Redox factor-1 (Ref-1), a redox signaling protein, regulates the DNA binding activity of several transcr...

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Literature Corpus work
cd28534c-dafb-5a3e-84a3-dfdefde79f30
DOI
10.21203/rs.3.rs-125304/v1
Open publication

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Ref-1 Redox Activity Alters Cancer Cell Metabolism in Pancreatic Cancer: Exploiting This Novel Finding as a Potential Target&nbsp;&nbsp;DOI 10.21203/rs.3.rs-125304/v1
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