Article

ERO1α promotes hypoxic tumour progression and is associated with poor prognosis in pancreatic cancer

2019-06-06

Abstract excerpt

Pancreatic cancer is a leading cause of mortality worldwide due to difficulty detecting early-stage disease and our poor understanding of the mediators that drive the progression of hypoxic solid tumours. We, therefore, used a heavy isotope ‘pulse/trace’ proteomic approach to determine how hypoxia alters pancreatic tumour expression of proteins that confer treatment resistance, promote metastasis, and suppress hos...

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Literature Corpus work: dd1846d1-aa84-50d1-9e6b-861d8e257fc0
DOI: 10.1101/662411

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