Article

Morphological profiling of all human and mouse miRNAs in 24M cells

2025-11-14

Abstract excerpt

MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression whose contributions to cell biology remain underexplored. Here, we used Cell Painting to quantify the morphological effect of 2,565 human and 1,900 mouse miRNA mimics on 24 million cells across five cell lines. To do so, we developed a novel single-cell morphological profiling analysis framework, involving stringent batch correction, feature...

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Literature Corpus work: cd1051d5-459d-5db3-af76-00a67b466a7a
DOI: 10.1101/2025.11.14.687149

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