Article
Synthetic Genome Shuffling of Poxviruses through Yeast for Next-Generation Oncolytic Platforms
2026-03-06
Abstract excerpt
<h4>ABSTRACT</h4> Oncolytic viruses (OVs) are promising cancer therapeutics that selectively infect and lyse tumor cells while sparing normal tissues and stimulating antitumor immunity. However, their efficacy remains limited by suboptimal cytolytic activity and insufficient immune stimulation, highlighting the need for improved designs. Here, we introduce a synthetic virology platform leveraging transformation-a...
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Identifiers and source
- Literature Corpus work
- cd0f37bc-6d17-5e0f-836c-ac86216b54aa
- DOI
- 10.64898/2026.03.06.710085