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Tumor Tropism of DNA Viruses for Oncolytic Virotherapy

16 Nov 2023

Abstract excerpt

Oncolytic viruses (OVs) have emerged as one of the most promising cancer immunotherapy agents that selectively target and kill cancer cells while sparing normal cells. OVs are from diverse families of viruses and can possess either a DNA or an RNA genome. These viruses also have either a natural or engineered tropism for cancer cells. Oncolytic DNA viruses have the additional advantage of a stable genome and...

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PMID: 38005938
DOI: 10.3390/v15112262

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