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Oncolytic Poxviruses

1 Oct 2014

Abstract excerpt

Current standard treatments of cancer can prolong survival of many cancer patients but usually do not effectively cure the disease. Oncolytic virotherapy is an emerging therapeutic for the treatment of cancer that exploits replication-competent viruses to selectively infect and destroy cancerous cells while sparing normal cells and tissues. Clinical and/or preclinical studies on oncolytic viruses have revealed...

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PMID: 25839047
DOI: 10.1146/annurev-virology-031413-085442

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