Article
Oncolytic Vesicular Stomatitis Virus: Optimisation Strategies for Anti-Cancer Therapies
31 Oct 2024
Abstract excerpt
Oncolytic viruses (OVs) represent a targeted anti-cancer therapy approach due to their ability not only to selectively infect and destroy malignant cells but also to induce an immune response. Vesicular stomatitis virus (VSV) offers a promising platform due to its low prevalence and pathogenicity in humans, lack of pre-existing immunity, easily manipulated genome, rapid growth to high titers in a broad range of...
