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Article

Molecular profiling of basal cell carcinomas in young patients.

BMC medical genomics - 20 Jul 2021

Abi Karam Marc, Kourie Hampig Raphael, Jalkh Nadine, Mehawej Cybel, Kesrouani Carole, Haddad Fady Gh, Feghaly Iman, Chouery Eliane, Tomb Roland

Abstract excerpt

BACKGROUND: Basal cell carcinoma (BCC) represents by far the most common non-melanoma skin cancer (NMSC) in the world with an increasing incidence of 3% to 10% per year, especially in patients under the age of 40. While variants in the sonic Hedgehog and cell cycle regulation pathways account for the majority of BCC cases in adults, the molecular etiology of BCC in young patients is unelucidated yet. This study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34284772
DOI: 10.1186/s12920-021-01030-w
PMCID: PMC8293576

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