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Article

Mutational landscape of basal cell carcinomas by whole-exome sequencing.

The Journal of investigative dermatology - 1 Jan 2014

Jayaraman Shyam S, Rayhan David J, Hazany Salar, Kolodney Michael S

Abstract excerpt

Recent advances in sequencing technology allow genome-scale approaches to cancer mutation discovery. Such data-intensive methods have been applied to cutaneous squamous cell carcinomas (SCCs) and melanomas but have not, to our knowledge, been applied to basal cell carcinomas (BCCs). We used whole-exome sequencing to characterize the mutational landscape of sporadic BCCs. We show that BCCs are the most mutated...

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Share to Aneuploidy
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23774526
DOI: 10.1038/jid.2013.276

Genes

PTCH1
CRNKL1
NEBL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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