Article

Enabling inference for context-dependent models of mutation by bounding the propagation of dependency

2021-12-16

Abstract excerpt

Although the rates at which positions in the genome mutate are known to depend not only on the nucleotide to be mutated, but also on neighboring nucleotides, it remains challenging to do phylogenetic inference using models of context-dependent mutation. In these models, the effects of one mutation may in principle propagate to faraway locations, making it difficult to compute exact likelihoods. This paper shows ho...

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Literature Corpus work: ccf0c6bd-591f-5a38-983b-42a6d54a1774
DOI: 10.1101/2021.12.15.472813

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