Article

Inhibition of CHK2 dependent DNA damage response suppresses Zika virus infection through a STING dependent mechanism

2022-10-03

Abstract excerpt

<h4>ABSTRACT</h4> Zika virus (ZIKV) is a mosquito-borne flavivirus that causes neurological disorders and microcephaly. Recent research has shown that ZIKV causes cell cycle arrest and DNA damage response in neuronal progenitor cells that potentially leads to congenital neurodevelopmental defects. However, the specific role of regulators that control DNA damage response to ZIKV infection and the related mechanism...

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Literature Corpus work: ccca72dc-93d9-522b-a3cb-95d48dcfa28a
DOI: 10.1101/2022.10.03.510601

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