Article

Redefining the topology of the human bone marrow using augmented spatial transcriptomic analysis

2025-12-23

Abstract excerpt

<h4>ABSTRACT</h4> The bone marrow (BM) is the main site of haematopoiesis in adult life. Our understanding of the pathogenesis of BM-derived blood cancers is limited by lack of spatial contextualisation. While emerging spatial transcriptomic (ST) platforms offer unprecedented opportunities for spatially-resolved cellular phenotyping, we recognise and incorporate the power of AI-based tissue feature detection to e...

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Literature Corpus work: 81dfaba1-b17c-5c20-955b-a1349583da1d
DOI: 10.64898/2025.12.22.694222

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