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Article

The role of sex and body weight on the metabolic effects of high-fat diet in C57BL/6N mice.

Nutrition & diabetes - 10 Apr 2017

Ingvorsen C, Karp N A, Lelliott C J

Abstract excerpt

BACKGROUND: Metabolic disorders are commonly investigated using knockout and transgenic mouse models on the C57BL/6N genetic background due to its genetic susceptibility to the deleterious metabolic effects of high-fat diet (HFD). There is growing awareness of the need to consider sex in disease progression, but limited attention has been paid to sexual dimorphism in mouse models and its impact in metabolic...

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Body Composition
Body Weight
Diet, High-Fat
Glucose Intolerance
Metabolic Diseases
Obesity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sex Characteristics

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PMID: 28394359
DOI: 10.1038/nutd.2017.6
PMCID: PMC5436097

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