Article

A Sparse Additive Model for High-Dimensional Interactions with an Exposure Variable

2018-10-16

Abstract excerpt

<h4>ABSTRACT</h4> A conceptual paradigm for onset of a new disease is often considered to be the result of changes in entire biological networks whose states are affected by a complex interaction of genetic and environmental factors. However, when modelling a relevant phenotype as a function of high dimensional measurements, power to estimate interactions is low, the number of possible interactions could be enorm...

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Literature Corpus work: cc2ea32a-1404-5707-8782-6a6a94cd6fd0
DOI: 10.1101/445304

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