Article

Changes in Protein <i>N</i> -Glycosylation Regulation Occur in the Human Parkinsonian Brain in a Region-Specific Manner

2022-05-20

Abstract excerpt

<h4>Summary</h4> Parkinson’s Disease (PD) associated state of neuroinflammation due to the aggregation of aberrant proteins is widely reported. One type of post-translational modification involved in protein stability is glycosylation. Here, we aimed to characterise the human Parkinsonian nigro-striatal N -glycome, and related transcriptome/proteome, and its correlation with endoplasmic reticulum stress and unfo...

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Literature Corpus work: cc0e948b-7691-5224-ba6d-0179f12b684f
DOI: 10.1101/2022.05.19.492623

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