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‘Off the shelf’ immunotherapies: Generation and application of pluripotent stem cell‐derived immune cells

1 Mar 2023

Abstract excerpt

In recent years, great strides have been made toward the development of immune cell-based therapies in the treatment of refractory malignancies. Primary T cells and NK cells armed with chimeric antigen receptors have achieved tremendous clinical success especially in patients with leukaemia and lymphoma. However, the autologous origin of these effector cells means that a single batch of laboriously engineered...

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PMID: 36855955
DOI: 10.1111/cpr.13425

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