Article

A comparative analysis of polyomaviruses Large Tumor Antigens reveals evolution of different importin α-dependent nuclear localization signals

2023-09-07

Abstract excerpt

<title>Abstract</title> <p>Nucleocytoplasmic transport is a fundamental eukaryotic process that regulates the passage of proteins between the nucleus and cytoplasm, crucial for maintaining cellular homeostasis, gene expression, and signal transduction. In the best characterized pathway, importin (IMP) α bridges cargoes bearing basic, classical nuclear localization signals (cNLSs) to IMPβ1, which mediates transpor...

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Literature Corpus work: cbea14b7-66e9-5de6-8142-d966642b4da1
DOI: 10.21203/rs.3.rs-3325828/v1

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