Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of the Mouse Polyomavirus Capsid Proteins with Importins Is Required for Efficient Import of Viral DNA into the Cell Nucleus.

Viruses - 31 Mar 2018

Soldatova Irina, Prilepskaja Terezie, Abrahamyan Levon, Forstová Jitka, Huérfano Sandra

Abstract excerpt

The mechanism used by mouse polyomavirus (MPyV) overcomes the crowded cytosol to reach the nucleus has not been fully elucidated. Here, we investigated the involvement of importin α/β1 mediated transport in the delivery of MPyV genomes into the nucleus. Interactions of the virus with importin β1 were studied by co-immunoprecipitation and proximity ligation assay. For infectivity and nucleus delivery assays, the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Transport
Share to Capsid Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fluorescent Antibody Technique

Share to Karyopherins

Share to Nuclear Localization Signals

Share to Polyomavirus

Share to Polyomavirus Infections

Share to Virus Assembly

Source

Open in PubMed Open full text

Identifiers

PMID: 29614718
DOI: 10.3390/v10040165
PMCID: PMC5923459

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of the Mouse Polyomavirus Capsid Proteins with Importins Is Required for Efficient Import of Viral DNA into the Cell Nucleus.PMID 29614718Read ↗

Specific interaction of capsid protein and importin-alpha/beta influences West Nile virus production.Semantic proximity Read ↗

Recombinant Adeno-Associated Virus Utilizes Host Cell Nuclear Import Machinery To Enter the NucleusSemantic proximity Read ↗

Uncoupling Uncoating of Herpes Simplex Virus Genomes from Their Nuclear Import and Gene ExpressionSemantic proximity Read ↗

Components of the LINC and NPC complexes coordinately target and translocate a virus into the nucleus to promote infectionSemantic proximity Read ↗

The polyomavirus major capsid protein VP1 interacts with the nuclear matrix regulatory protein YY1.Semantic proximity Read ↗

Nuclear entry and CRM1-dependent nuclear export of the Rous sarcoma virus Gag polyprotein.Semantic proximity Read ↗

Nuclear Import of Epstein-Barr virus BLLF2 is Mediated by an Importin β1-Dependent MechanismSemantic proximity Read ↗

CRM1 Promotes Capsid Disassembly and Nuclear Envelope Translocation of Adenovirus Independently of Its Export Function.Semantic proximity Read ↗

Importin-beta family members mediate alpharetrovirus gag nuclear entry via interactions with matrix and nucleocapsid.Semantic proximity Read ↗

Role of a nuclear localization signal on the minor capsid Proteins VP2 and VP3 in BKPyV nuclear entrySemantic proximity Read ↗

A Ran-binding protein facilitates nuclear import of human papillomavirus type 16Semantic proximity Read ↗

The VP1 subunit of JC polyomavirus recapitulates early events in viral trafficking and is a novel tool to study polyomavirus entrySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.