Article

Elevated Plasma Complement Factors in<i>CRB1</i>-associated Inherited Retinal Dystrophies

2023-11-10

Abstract excerpt

<h4>Objective</h4> To determine the profile of inflammation-related proteins and complement system factors in serum of CRB1 -associated inherited retinal dystrophies ( CRB1 -IRDs). <h4>Design</h4> A case-control study. <h4>Subjects, Participants, and/or Controls</h4> A cohort of 30 Dutch CRB1 -IRD patients and 29 Dutch healthy controls (HC) (Cohort I), and a second cohort of 123 CRB1 -IRD patients from 14 countrie...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: cbaf7498-2ec6-5b45-81fd-823eae02c1a6
DOI: 10.1101/2023.11.10.23298334

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Elevated Plasma Complement Factors in<i>CRB1</i>-associated Inherited Retinal DystrophiesDOI 10.1101/2023.11.10.23298334Read

Elevated Plasma Complement Factors in CRB1-Associated Inherited Retinal Dystrophies.Semantic proximity Read

Unveiling Inflammation-Like Retinal Remodeling in CRB1-Associated Inherited Retinal Dystrophies: Insights From a Multicenter Study.Semantic proximity Read

CRB1-Associated Retinal Dystrophies: Genetics, Clinical Characteristics, and Natural History.Semantic proximity Read

CRB1 mutations in inherited retinal dystrophies.Semantic proximity Read

The Functional Effect of Rare Variants in Complement Genes on C3b Degradation in Patients With Age-Related Macular Degeneration.Semantic proximity Read

Clinical and mutational signatures of CRB1-associated retinopathies: a multicentre study.Semantic proximity Read

Clinical and Genetic Spectrum of a Large Cohort With Total and Sub-total Complement DeficienciesSemantic proximity Read

Pathogenicity Analysis of Two Novel CRB1 Mutations in Three Chinese Inherited Retinal Dystrophy Families and a Literature Review.Semantic proximity Read

Phenotypic features of CRB1-associated early-onset severe retinal dystrophy and the different molecular approaches to identifying the disease-causing variants.Semantic proximity Read

Complement System Proteins in the Human Aqueous Humor and Their Association with Primary Open-Angle GlaucomaSemantic proximity Read

Complement factor I: Regulatory nexus, driver of immunopathology, and therapeutic.Semantic proximity Read

Rare complement factor I variants associated with reduced macular thickness and age-related macular degeneration in the UK Biobank.Semantic proximity Read