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Antibody correlates of protection for Ebola virus infection : effects of mutations within the viral glycoprotein on immune escape

2019-01-01

Abstract excerpt

Ebola virus (EBOV) is an enveloped, single-stranded RNA virus that can cause Ebola virus disease (EVD), a highly lethal illness with up to 90% mortality. It is thought that EVD survivors are protected against subsequent infection with EBOV and that neutralising antibodies to the viral surface glycoprotein (GP) are potential correlates of protection. Serological studies are vital to assess neutralising antibodies t...

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Literature Corpus work
cb3e52aa-ffaf-5359-a17f-83e14c29a4ba
DOI
10.17638/03043891
Open publication

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Antibody correlates of protection for Ebola virus infection : effects of mutations within the viral glycoprotein on immune escapeDOI 10.17638/03043891
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