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Detection and Quantification of Antibody to SARS-CoV-2 Receptor Binding Domain Provides Enhanced Sensitivity, Specificity and Utility

2021-01-05

Abstract excerpt

Background: Accurate and sensitive detection of antibody to SARS-CoV-2 remains an essential component of the pandemic response. Measuring antibody that predicts neutralising activity and the vaccine response is an absolute requirement for laboratory-based confirmatory and reference activity.<br><br>Methods: The viral receptor binding domain (RBD) constitutes the prime target antigen for neutralising antibody. A do...

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Literature Corpus work
631e2167-3da9-51ab-bd59-069f0a2be78f
DOI
10.2139/ssrn.3739821
Open publication

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