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Biologically contained Ebola virus enables standardised neutralisation testing for preclinical and clinical immunogenicity assessment

2026-02-07

Abstract excerpt

<h4>Summary</h4> <h4>Background</h4> Neutralising antibody titres are widely used as key immunogenicity endpoints in Ebola virus (EBOV) vaccine and monoclonal antibody clinical trials. However, direct comparison of results across studies remains challenging due to the use of heterogeneous neutralisation platforms, ranging from pseudotyped viruses to live EBOV assays. These limitations restrict assay standardisat...

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Literature Corpus work
b0618744-4585-5e50-8755-ff9dd916fc13
DOI
10.64898/2026.02.06.26345727
Open publication

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Biologically contained Ebola virus enables standardised neutralisation testing for preclinical and clinical immunogenicity assessmentDOI 10.64898/2026.02.06.26345727
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