Article

NCoA3 upregulation in breast cancer-associated adipocytes elicits an inflammatory profile

2022-06-28

Abstract excerpt

<h4>Purpose: </h4> NCoA3 is a transcriptional coactivator of NF-κB and other factors, present in undetectable levels into normal cells and amplified or overexpressed in several types of cancer, including breast tumors. We have previously demonstrated that NCoA3 levels decrease during adipogenesis, but its role in tumor-surrounding adipose tissue is still unknown. Therefore, in this work, we studied the modulation...

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Literature Corpus work: cb1cb6d4-2ab5-5235-b507-0bd63ff39d4b
DOI: 10.21203/rs.3.rs-1730698/v2

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