Article
Cancer-associated adipocytes: emerging supporters in breast cancer.
Journal of experimental & clinical cancer research : CR - 12 Aug 2020
Zhao Chongru, Wu Min, Zeng Ning, Xiong Mingchen, Hu Weijie, Lv Wenchang, Yi Yi, Zhang Qi, Wu Yiping
Abstract excerpt
Breast cancer (BC) is a malignant breast tumor confronted with high invasion, metastasis and recurrence rate, and adipocytes are the largest components in breast tissue. The aberrant adipocytes, especially the BC-neighbored cancer-associated adipocytes (CAAs), are found in the invasive front of BC. CAAs present a vicious phenotype compared with mature mammary adipocytes and mediate the crosstalk network between...
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