Article

Targeting cancer-associated adipocyte-derived CXCL8 inhibits triple-negative breast cancer progression and enhances the efficacy of anti-PD-1 immunotherapy

2023-01-24

Abstract excerpt

<title>Abstract</title> <p>Cancer-associated adipocytes (CAAs), one of the primary stromal components, exhibit intimate crosstalk and release multiple cell factors mediating local and systemic biological effects. However, the role of CAAs in the regulation of systemic immune responses and their potential value in the clinical treatment of triple-negative breast cancer (TNBC) are not well described. Transcriptome...

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Literature Corpus work: 06566e69-daf4-51f3-8b7d-8fd1ee41c5ef
DOI: 10.21203/rs.3.rs-2419604/v1

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