Article

YAP Manipulates Proliferation Via PTEN/AKT/mTOR-mediated Autophagy in Lung Adenocarcinomas

2020-09-22

Abstract excerpt

<title>Abstract</title> <p>Background: Autophagy is a double-edged sword during the initiation or progression of multiple tumors. Hippo pathway core-factor YAP has been proved to be involved in autophagy processes. The present study aimed to identify the mechanism underlying modulation of YAP via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas (LUAD). <h4>Methods:</h4> Data of LUAD chip GSE43458 was obta...

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Literature Corpus work: cb023cdd-a84c-5be9-b886-e84cb0efc8b3
DOI: 10.21203/rs.3.rs-78208/v1

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