Article

The circadian clock gene ARNTL overexpression suppresses oral cancer progression by inducing apoptosis via activating autophagy

2022-07-06

Abstract excerpt

<title>Abstract</title> <p><bold>Objective</bold> The study aimed to explore tumor suppressor mechanism of ARNTL from the perspective of autophagy in oral cancer <bold>Methods</bold> Human oral squamous carcinoma HN6 cells stably overexpressing ARNTL were established, cell viability and apoptosis were detected by CCK-8 and TUNEL assays, and intracellular autophagosomes were observed under electron microscopy. Wes...

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Literature Corpus work: 46604da8-dacb-561f-857f-87d089ab19b2
DOI: 10.21203/rs.3.rs-1811176/v1

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