Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of FOXOs and autophagy in cancer and metastasis—Implications in therapeutic development

31 May 2020

Abstract excerpt

Autophagy is a highly conserved intracellular degradation process that plays a crucial role in cell survival and stress reactions as well as in cancer development and metastasis. Autophagy process involves several steps including sequestration, fusion of autophagosomes with lysosomes and degradation. Forkhead box O (FOXO) transcription factors regulate the expression of genes involved in cellular metabolic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to FOXO transcription factor regulation
Share to Sirtuins and Resveratrol in Medicine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32474970
DOI: 10.1002/med.21695

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of FOXOs and autophagy in cancer and metastasis—Implications in therapeutic developmentPMID 32474970Read ↗

FOXO transcription factor family in cancer and metastasisSemantic proximity Read ↗

Molecular Mechanisms of Autophagy in Cancer Development, Progression, and TherapySemantic proximity Read ↗

Role of FOXO Transcription Factors in Cancer Metabolism and AngiogenesisSemantic proximity Read ↗

Dissecting the multifaceted roles of autophagy in cancer initiation, growth, and metastasis: from molecular mechanisms to therapeutic applicationsSemantic proximity Read ↗

Autophagy and its role in osteosarcomaSemantic proximity Read ↗

Unravelling the multifaceted roles of Atg proteins to improve cancer therapySemantic proximity Read ↗

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulationSemantic proximity Read ↗

Targeting Autophagy Using Long Non-Coding RNAs (LncRNAs): New Landscapes in the Arena of Cancer TherapeuticsSemantic proximity Read ↗

Autophagy and autophagy-related proteins in cancerSemantic proximity Read ↗

Autophagy-Modulating Long Non-coding RNAs (LncRNAs) and Their Molecular Events in CancerSemantic proximity Read ↗

Re-evaluating the role of FOXOs in cancerSemantic proximity Read ↗

Critical role of FOXO3a in carcinogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.